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Cardiac drug safety : a bench to bedside approach

[NT 42944] Record Type:	[NT 8598] Electronic resources : [NT 40817] monographic
[NT 47348] Title Information:	a bench to bedside approach
[NT 47261] Author:	KilleenMatthew J.,
[NT 47351] Place of Publication:	Singapore
[NT 47263] Published:	World Scientific;
[NT 47352] Year of Publication:	2012
[NT 47264] Description:	1 online resource (189 p.)
[NT 47266] Subject:	Arrhythmia - Treatment -
[NT 47266] Subject:	Drugs - Safety regulations - Canada -
[NT 47266] Subject:	Heart - drug effects -
[NT 47266] Subject:	Drug Toxicity - prevention & control -
[NT 47266] Subject:	Electronic books -
[NT 51458] Online resource:	http://www.worldscientific.com/worldscibooks/10.1142/7839#t=toc
[NT 47265] Notes:	Variability of repolarization
[NT 51398] Summary:	Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape. Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, curr
[NT 50961] ISBN:	9789814317467electronic bk.
[NT 50961] ISBN:	9814317462electronic bk.
[NT 50961] ISBN:	1280669225
[NT 50961] ISBN:	9781280669224
[NT 60779] Content Note:	Foreword; "Et causae quoque aestimatio saepe morbum solvit"* [Celsus: Prooemium 69, De Medicina]; Preface; Chapter 1 Challenges Facing the Pharmaceutical Industry in the 21st Century; Introduction; The Impact of Cardiac Toxicity on the Pharmaceutical Industry; References; Chapter 2 The Cellular Basis of Cardiac Electrophysiology; Introduction; The Initiation of the Heart Beat; The Ventricular Cardiac Action Potential; The Relationship Between the Cardiac Action Potential and the Electrocardiogram; Ion Channels Underlying the Cardiac Action Potential; Sodium channels

Cardiac drug safety : a bench to bedside approach
Killeen, Matthew J.

Cardiac drug safety : a bench to bedside approach / Matthew J. Killeen - Singapore : World Scientific, 2012. - 1 online resource (189 p.).
Foreword; "Et causae quoque aestimatio saepe morbum solvit"* [Celsus: Prooemium 69, De Medicina]; Preface; Chapter 1 Challenges Facing the Pharmaceutical Industry in the 21st Century; Introduction; The Impact of Cardiac Toxicity on the Pharmaceutical Industry; References; Chapter 2 The Cellular Basis of Cardiac Electrophysiology; Introduction; The Initiation of the Heart Beat; The Ventricular Cardiac Action Potential; The Relationship Between the Cardiac Action Potential and the Electrocardiogram; Ion Channels Underlying the Cardiac Action Potential; Sodium channels.
Variability of repolarizationDescription based on print version record.
ISBN 9789814317467ISBN 9814317462ISBN 1280669225ISBN 9781280669224
ArrhythmiaDrugsHeartDrug ToxicityElectronic books -- Treatment -- Safety regulations -- drug effects -- prevention & control -- Canada

Cardiac drug safety : a bench to bedside approach
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