• Trends on the role of PET in drug development
  • 紀錄類型: 書目-電子資源 : 單行本
    作者: ElsingaPhilip H.,
    其他作者: Van WaardeAren,
    其他作者: PaansAnne M. J.,
    出版地: Singapore
    出版者: World Scientific;
    出版年: 2012
    面頁冊數: 1 online resource (799 p.)
    標題: Drug Design -
    標題: Technology, Pharmaceutical -
    標題: Positron-Emission Tomography -
    標題: Drug development -
    標題: Tomography, Emission -
    標題: Pharmaceutical technology -
    標題: Electronic books -
    電子資源: http://www.worldscientific.com/worldscibooks/10.1142/7851#t=toc
    附註: 2.2 Influence of ionic liquid and tertiary alcohols on [18F]fluorination
    摘要註: Drug development is very expensive and a fight against time. PET offers possibilities to speed up this process by adding unique in vivo information on pharmacokinetics/dyclmics of a drug at an early stage. This information can help decision makers to move the drug in the drug development process or to decide to stop further developments. This unique and complete book highlights the different ways PET can be used and describes the latest trends in the various disciplines within nuclear medicine to further improve methodologies and increase the number of tools to accelerate drug development. Var
    ISBN: 9789814317740electronic bk.
    ISBN: 9814317748electronic bk.
    內容註: The Editors; Contributors; Preface; 1 Introduction on PET. Description of Basics and Principles Aren van Waarde; References; 2 Drug Development in the Pharmaceutical Industry Adrian D. Nunn; 1. Introduction; 2. Drug Approval Rates; 3. Costs of Each Stage; 4. Efficiency of Drug Development; 5. Changing Healthcare Model; 6. Comparative Effectiveness; 7. Personalized Medicine; 8. Regulatory Issues; 9. Conclusions; References; 3 Molecular Imaging Biomarkers as a Tool in Development of Novel Medicines R. Paul Maguire; 1. Summary
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