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Affinity and efficacy : the components of drug-receptor interactions

[NT 42944] Record Type:	[NT 8598] Electronic resources : [NT 40817] monographic
[NT 47348] Title Information:	the components of drug-receptor interactions
[NT 47261] Author:	EhlertFrederick J.,
[NT 47351] Place of Publication:	New Jersey
[NT 47263] Published:	World Scientific;
[NT 47352] Year of Publication:	2014
[NT 47264] Description:	1 online resource
[NT 47266] Subject:	Drug receptors -
[NT 47266] Subject:	Drugs - Effectiveness -
[NT 47266] Subject:	Drug-nutrient interactions -
[NT 47266] Subject:	Pharmaceutical chemistry -
[NT 47266] Subject:	Receptors, Drug -
[NT 47266] Subject:	Ligand-Gated Ion Channels -
[NT 47266] Subject:	Protein Binding -
[NT 47266] Subject:	Radioligand Assay -
[NT 47266] Subject:	Receptors, G-Protein-Coupled -
[NT 51458] Online resource:	http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc
[NT 47265] Notes:	Print version record
[NT 50961] ISBN:	9789814324229electronic bk.
[NT 50961] ISBN:	9814324221electronic bk.
[NT 60779] Content Note:	Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors

Affinity and efficacy : the components of drug-receptor interactions
Ehlert, Frederick J.

Affinity and efficacy : the components of drug-receptor interactions / Frederick J. Ehlert - New Jersey : World Scientific, 2014. - 1 online resource.
Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
Print version record.
Includes bibliographical references.
ISBN 9789814324229ISBN 9814324221
Drug receptorsDrugsDrug-nutrient interactionsPharmaceutical chemistryReceptors, DrugLigand-Gated Ion ChannelsProtein BindingRadioligand AssayReceptors, G-Protein-Coupled -- Effectiveness

Affinity and efficacy : the components of drug-receptor interactions
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